How to See Really Tiny Things Without Killing Them

Head to https://linode.com/scishow to get a $100 60-day credit on a new Linode account. Linode offers simple, affordable, and accessible Linux cloud solutions and services.

Where would biology be without microscopes? But for a long time, in order to see the smallest bits of life, that life had to be dead. Then along came Atomic Force Microscopy, which let us observe things like DNA and proteins moving around in real time.

Hosted by: Reid Reimers (he/him)
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Matt Curls, Alisa Sherbow, Dr. Melvin Sanicas, Harrison Mills, Adam Brainard, Chris Peters, charles george, Piya Shedden, Alex Hackman, Christopher R, Boucher, Jeffrey Mckishen, Ash, Silas Emrys, Eric Jensen, Kevin Bealer, Jason A Saslow, Tom Mosner, Tomás Lagos González, Jacob, Christoph Schwanke, Sam Lutfi, Bryan Cloer
----------
Looking for SciShow elsewhere on the internet?
SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/
TikTok: https://www.tiktok.com/@scishow
Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishowFacebook: http://www.facebook.com/scishow

#SciShow #science #education #learning #complexly
----------
Sources:
http://www.wmii.uwm.edu.pl/~kulesza/wp-content/uploads/2012.Technical.Sciences.Bramowicz.Kulesza.15_2.pdf
https://advanced-microscopy.utah.edu/education/electron-micro/
https://afm.oxinst.com/modes/scanning-tunneling-microscopy-stm
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0428-0
https://www.mdpi.com/2079-6374/12/12/1116
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660199/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700051/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899716/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457988/
https://www.pnas.org/doi/10.1073/pnas.2015728118

Image Sources:
https://www.gettyimages.com/detail/video/protozoa-protists-unicellular-organism-under-microscope-stock-footage/1371421170
https://flickr.com/photos/oakridgelab/44670612800/in/photolist-stSbmH-o19UQG-2e8y9Dz-7yKzAS-2b4oyTj-76YBhz-76YTwR
https://commons.wikimedia.org/wiki/File:AFM-IR_%26_s%E2%80%91SNOM_NT-MDT_microscope.jpg
https://commons.wikimedia.org/wiki/File:Titian_Girolamo_FracastoroFXD.jpg
https://www.gettyimages.com/detail/video/scientist-using-microscope-in-lab-stock-footage/1337804651
https://www.gettyimages.com/detail/video/human-hair-under-microscopy-stock-footage/938505412
https://www.gettyimages.com/detail/video/macro-footage-of-flowing-blood-cells-magnified-under-stock-footage/1353566232
https://www.gettyimages.com/detail/video/sharp-beams-from-lens-edges-stock-footage/1338300131
https://www.gettyimages.com/detail/illustration/waves-diffraction-royalty-free-illustration/507567826?phrase=diffraction+of+waves&adppopup=true
https://www.gettyimages.com/detail/illustration/vector-diagram-with-the-ultraviolet-light-royalty-free-illustration/1372178648?phrase=wavelength+400+nanometer&adppopup=true
https://www.gettyimages.com/detail/video/light-leaks-4k-footage-for-projects-optical-glow-lens-stock-footage/1414227141
https://www.gettyimages.com/detail/video/on-the-microscope-lens-manually-close-the-diaphragm-to-stock-footage/898417938
https://en.wikipedia.org/wiki/File:Scanning_Electron_Microscope.ogv
https://www.flickr.com/photos/niaid/5950870236/in/album-72157682564763213/
https://www.flickr.com/photos/niaid/49727106598/in/album-72157682564763213/
https://commons.wikimedia.org/wiki/File:12985_2019_1268_Fig10B_HTML.png
https://commons.wikimedia.org/wiki/File:Diatom_of_La_Tembladera_wetland.tif
https://commons.wikimedia.org/wiki/File:NTEGRA_Spectra_II_and_measuring_heads.jpg
https://commons.wikimedia.org/wiki/File:%D0%90%D0%BA%D1%82%D0%B8%D0%B2%D0%BD%D1%8B%D0%B9_%D1%82%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82.png
https://www.gettyimages.com/detail/video/human-blood-diseases-interstitial-fluid-bacterial-stock-footage/1340677173
https://pubs.acs.org/doi/10.1021/acs.nanolett.0c04465
https://www.gettyimages.com/detail/video/concept-of-covid-19-or-2019-ncov-coronavirus-stock-footage/1212139003
https://royalsocietypublishing.org/doi/10.1098/rsob.140046
https://commons.wikimedia.org/wiki/File:AFM_at_work.jpg
https://pubs.aip.org/aip/rsi/article/92/3/033705/1061603/Faster-high-speed-atomic-force-microscopy-for
https://www.gettyimages.com/detail/video/virus-cell-stock-footage/1043393556
https://commons.wikimedia.org/wiki/File:Mechanics-of-epithelial-closure-over-non-adherent-environments-ncomms7111-s11.ogv
https://commons.wikimedia.org/wiki/File:AFM_(used)_cantilever_in_Scanning_Electron_Microscope,_magnification_1000x.GIF
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0428-0/figures/4
https://www.gettyimages.com/detail/video/cancer-cells-stock-footage/1405577905